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Article

Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas.

Cancer letters - 8 Jun 2004

Nikiforova Marina N, Ciampi Raffaele, Salvatore Giuliana, Santoro Massimo, Gandhi Manoj, Knauf Jeffrey A, Thomas Gerry A, Jeremiah Stephen, Bogdanova Tatyana I, Tronko Mykola D, Fagin James A, Nikiforov Yuri E

Abstract excerpt

Point mutations of the BRAF gene have been recently described with high prevalence in papillary thyroid carcinomas. However, this molecular alteration has not been studied in radiation-induced thyroid tumors. We analyzed the prevalence of BRAF point mutations and RET/PTC rearrangements in 55 post-Chernobyl papillary carcinomas, compared with 82 sporadic papillary carcinomas. Radiation-induced tumors demonstrated...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

Share to Proto-Oncogene Proteins c-raf

Share to Proto-Oncogene Proteins c-ret

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Source

Identifiers

PMID: 15145515
DOI: 10.1016/j.canlet.2003.12.004

Genes

BRAF
RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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