Article
Regulation of proinflammatory mediator production in RAW264.7 macrophage by Vibrio vulnificus luxS and smcR.
FEMS immunology and medical microbiology - 1 Jun 2004
Shin Na-Ri, Lee Deog-Yong, Shin Sung Jae, Kim Kun-Soo, Yoo Han-Sang
Abstract excerpt
Vibrio vulnificus causes fatal septicemia in human hosts, which is the consequence of raw shellfish consumption. The mortality following septicemia is dependent on the in vivo production of inflammatory mediators, including tumor necrosis factor-alpha (TNFalpha). The present study was set up to investigate the association of quorum sensing in V. vulnificus with the host immune response. The effect of quorum...
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