Article
Differential expression of cytokine genes in THP-1-derived macrophages infected with mild and virulence strains of Shigella flexneri 2a.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Nov 2020
Shabani Nor Raihan Mohammad, Mokhtar Munirah, Leow Chiuan Herng, Lean Qi Ying, Chuah Candy, Singh Kirnpal Kaur Banga, Leow Chiuan Yee
Abstract excerpt
Shigella is an intracellular bacterial pathogen that causes bacterial dysentery called shigellosis. The assessment of pro- and anti-inflammatory mediators produced by immune cells against this bacteria are vital in identifying the effectiveness of the immune reaction in protecting the host. In Malaysia, Shigella is ranked as the third most common bacteria causing diarrheal disease among children below 5 years...
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