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Article

Genomic Structure and Characterization of the 5′-Flanking Region of the Human Ghrelin Gene

18 May 2004

Abstract excerpt

Ghrelin, an endogenous ligand for the GH secretagogue receptor, induces GH secretion, food intake, and positive energy balance. Although ghrelin exhibits a variety of hormonal actions, the mechanisms regulating ghrelin expression and secretion remain unclear. To understand regulation of human ghrelin gene expression, we examined the genomic structure of approximately 5,000 bp of the 5'-flanking region of the...

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PMID: 15142980
DOI: 10.1210/en.2003-1718

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