Article
Talin B is required for force transmission in morphogenesis of Dictyostelium.
The EMBO journal - 2 Jun 2004
Tsujioka Masatsune, Yoshida Kunito, Inouye Kei
Abstract excerpt
Talin plays a key role in the assembly and stabilisation of focal adhesions, but whether it is directly involved in force transmission during morphogenesis remains to be elucidated. We show that the traction force of Dictyostelium cells mutant for one of its two talin genes talB is considerably smaller than that of wild-type cells, both in isolation and within tissues undergoing morphogenetic movement. The...
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