Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Disruption of the Actin Cytoskeleton Can Complement the Ability of Nef To Enhance Human Immunodeficiency Virus Type 1 Infectivity

12 May 2004

Abstract excerpt

The human immunodeficiency virus (HIV) protein Nef has been shown to increase the infectivity of HIV at an early point during infection. Since Nef is known to interact with proteins involved in actin cytoskeleton rearrangements, we tested the possibility that Nef may enhance HIV infectivity via a mechanism that involves the actin cytoskeleton. We find that disruption of the actin cytoskeleton complements the Nef...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV/AIDS drug development and treatment
Share to HIV Research and Treatment
Share to Syphilis Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15140972
DOI: 10.1128/jvi.78.11.5745-5755.2004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Disruption of the Actin Cytoskeleton Can Complement the Ability of Nef To Enhance Human Immunodeficiency Virus Type 1 InfectivityPMID 15140972Read ↗

How HIV Takes Advantage of the Cytoskeleton in Entry and ReplicationSemantic proximity Read ↗

How HIV Nef Proteins Hijack Membrane Traffic To Promote InfectionSemantic proximity Read ↗

Human Immunodeficiency Virus Type 1 Nef Functions at the Level of Virus Entry by Enhancing Cytoplasmic Delivery of VirionsSemantic proximity Read ↗

HIV ‐1 Nef: Taking Control of Protein TraffickingSemantic proximity Read ↗

HIV Infection: Shaping the Complex, Dynamic, and Interconnected Network of the CytoskeletonSemantic proximity Read ↗

The host cytoskeleton: a key regulator of early HIV ‐1 infectionSemantic proximity Read ↗

Human Immunodeficiency Virus Type 1 Nef: Adapting to Intracellular Trafficking PathwaysSemantic proximity Read ↗

All-Round Manipulation of the Actin Cytoskeleton by HIVSemantic proximity Read ↗

Dissociation of the CD4 downregulation and viral infectivity enhancement functions of human immunodeficiency virus type 1 NefSemantic proximity Read ↗

Establishment of a Functional Human Immunodeficiency Virus Type 1 (HIV-1) Reverse Transcription Complex Involves the CytoskeletonSemantic proximity Read ↗

Human immunodeficiency virus (HIV)-1 proteins and cytoskeleton: partners in viral life and host cell deathSemantic proximity Read ↗

Get in and get out: Remodeling of the cellular actin cytoskeleton upon HIV‐1 infectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.