Genomic analysis of anaerobic respiration in the archaeon Halobacterium sp. strain NRC-1: dimethyl sulfoxide and trimethylamine N-oxide as terminal electron acceptors.

Abstract excerpt

We have investigated anaerobic respiration of the archaeal model organism Halobacterium sp. strain NRC-1 by using phenotypic and genetic analysis, bioinformatics, and transcriptome analysis. NRC-1 was found to grow on either dimethyl sulfoxide (DMSO) or trimethylamine N-oxide (TMAO) as the sole terminal electron acceptor, with a doubling time of 1 day. An operon, dmsREABCD, encoding a putative regulatory protein,...

Topics

• Anaerobiosis
• Chromosome Mapping
• Dimethyl Sulfoxide
• Gene Deletion
• Halobacterium
• Methylamines
• Mutation
• Oligonucleotide Array Sequence Analysis
• Oxidoreductases
• Phylogeny
• Transcription, Genetic