Article
A novel polymorphism of FcalphaRI (CD89) associated with aggressive periodontitis.
Tissue antigens - 1 Jun 2004
Kaneko S, Kobayashi T, Yamamoto K, Jansen M D, van de Winkel J G J, Yoshie H
Abstract excerpt
Immunoglobulin A Fc receptor (FcalphaRI) has been implicated in the pathogenesis of periodontitis, because increased IgA responses and FcalphaRI-bearing neutrophils are observed in the disease lesions. Inter-individual differences in susceptibility to periodontitis may be attributable to genetic variability in FcalphaRI-mediated immunity. We here identified an FcalphaRI novel polymorphism (nt 324 A-to-G...
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