Article
Fc gamma receptor genes as risk markers for localized aggressive periodontitis in African-Americans.
Journal of periodontology - 1 May 2002
Fu Yali, Korostoff Jonathan M, Fine Daniel H, Wilson Mark E
Abstract excerpt
BACKGROUND: Receptors for the Fc fragment of immunoglobulin G (Fc gammaRs) play a crucial role in host defense against bacterial infection by linking humoral and cell-mediated immune responses. Allelic variants of certain Fc gammaRs have been shown to differ relative to their biologic activity. Thus, genes encoding allotypes with diminished activity have been suggested as potential risk factors for infectious...
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