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Article

Molecular heterogeneity in AML/MDS patients with 3q21q26 rearrangements

21 Apr 2004

Abstract excerpt

Patients with 3q21q26 rearrangements seem to share similar clinicopathologic features and a common molecular mechanism, leading to myelodysplasia or acute myeloid leukemia (AML). The ectopic expression of EVI1 (3q26) has been implicated in the dysplasia that characterizes this subset of myeloid neoplasias. However, lack of EVI1 expression has been reported in several cases, and overexpression of EVI1 was detected...

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PMID: 15138998
DOI: 10.1002/gcc.20033

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Molecular heterogeneity in AML/MDS patients with 3q21q26 rearrangementsPMID 15138998Read ↗

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