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Article

3q26.2/EVI1 rearrangement is associated with poor prognosis in classical Philadelphia chromosome-negative myeloproliferative neoplasms.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jul 2017

Hu Zhihong, Medeiros L Jeffrey, Wang Wei, Chen Zi, Tang Guilin, Hodjat Parsa, Yang Su, Fang Lianghua, Li Yan, Verstovsek Srdan, Hu Shimin

Abstract excerpt

Classical Philadelphia chromosome-negative myeloproliferative neoplasms are a group of closely related myeloid disorders with different histologic features and clinical presentations at an early stage, but all later develop into a similar fibrotic stage with variable risk of acute transformation. The significance of 3q26.2/EVI1 rearrangement has been well recognized in acute myeloid leukemia, myelodysplastic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28338652
DOI: 10.1038/modpathol.2017.19

Genes

JAK2

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