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Article

Increased expression of antioxidant enzymes in radioresistant variant from U251 human glioblastoma cell line

1 Jun 2004

Abstract excerpt

Glioblastoma is one of the most radioresistant tumors. Exposure of cells to ionizing radiation leads to formation of reactive oxygen species (ROS) that are associated with radiation-induced cytotoxicity. ROS scavengers, therefore, are one of the important factors in protecting cells against ROS injury during ionizing radiation exposure. In the present study, we isolated and established a radioresistant variant...

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PMID: 15138630
DOI: 10.3892/ijmm.13.6.883

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