Article
VHY, a novel myristoylated testis-restricted dual specificity protein phosphatase related to VHX.
The Journal of biological chemistry - 30 Jul 2004
Alonso Andres, Narisawa Sonoko, Bogetz Jori, Tautz Lutz, Hadzic Radinka, Huynh Huong, Williams Scott, Gjörloff-Wingren Anette, Bremer Meire C D, Holsinger Leslie J, Millan José L, Mustelin Tomas
Abstract excerpt
The human DUSP15 gene encodes an uncharacterized 235-amino acid member of the subfamily of small dual specificity protein phosphatases related to the Vaccinia virus VH1 phosphatase. Similar to VHR-related MKPX (VHX) (DUSP22), the predicted protein has an N-terminal myristoylation recognition sequence, and we show here that both are indeed modified by the attachment of a myristate to Gly-2. In recognition of this...
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