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Article

Characterization of the conformational state and flexibility of HIV-1 glycoprotein gp120 core domain.

The Journal of biological chemistry - 16 Jul 2004

Pan Yongping, Ma Buyong, Keskin Ozlem, Nussinov Ruth

Abstract excerpt

gp120 is key to the human immunodeficiency virus type 1 viral cell entry. Knowledge of the detailed conformational states of gp120 is crucial to intervention, yet the unbound form is still resistant to structural characterization probably because of its flexibility. Toward this goal, we performed molecular dynamics simulations on the wild type gp120 core domain extracted from its ternary crystal structure and on...

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Share to Amino Acid Motifs
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15131118
DOI: 10.1074/jbc.M404364200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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