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Article

Association of the lipoprotein lipase gene Ser447Ter polymorphism with hypertension and blood pressure variation: evidence from an updated meta-analysis.

Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2017

Wang June, Du Shenlin, Wang Jiamin, Zhu Man, Wen Xue, Yang Weiqing

Abstract excerpt

The polymorphism of lipoprotein lipase (LPL) gene Ser447Ter (S447X) has long been linked to hypertension and blood pressure variation, but the established data remained controversial. To better elucidate this inconsistency, a meta-analysis was conducted. We comprehensively searched electronic databases, including Pubmed, EMBASE, China National Knowledge Infrastructure (CNKI), Web of Science, for all literatures...

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Source

Identifiers

PMID: 28640651
DOI: 10.1080/10641963.2017.1313848

Genes

LPL

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Association of the lipoprotein lipase gene Ser447Ter polymorphism with hypertension and blood pressure variation: evidence from an updated meta-analysis.PMID 28640651Read ↗

Meta-based association of the lipoprotein lipase gene S447X variant with hypertension and blood pressure variation.Semantic proximity Read ↗

Associations of the LPL S447X and Hind III Polymorphism with Type 2 Diabetes Mellitus Risk: A Meta-Analysis.Semantic proximity Read ↗

Lipoprotein lipase gene polymorphisms and blood pressure levels in the Northern Chinese Han population.Semantic proximity Read ↗

Study of Common Genetic Variant S447X in Lipoprotein Lipase and Its Association with Lipids and Lipoproteins in Type 2 Diabetic PatientsSemantic proximity Read ↗

Association between ApoE polymorphism and hypertension: A meta-analysis of 28 studies including 5898 cases and 7518 controls.Semantic proximity Read ↗

[Association and linkage analysis between the S447X polymorphism of LPL gene and serum lipids, blood pressures in twins].Semantic proximity Read ↗

[The association of S447X and Hind III polymorphism in the lipoprotein lipase gene with dyslipidemia of the metabolic syndrome in patients with essential hypertension].Semantic proximity Read ↗

The HindIII and PvuII polymorphisms of lipoprotein lipase (LPL) gene reduce the risk of ischemic stroke (IS): A meta-analysis.Semantic proximity Read ↗

The LPL S447X cSNP is associated with decreased blood pressure and plasma triglycerides, and reduced risk of coronary artery disease.Semantic proximity Read ↗

The S447X variant of lipoprotein lipase gene is associated with metabolic syndrome and lipid levels among Turks.Semantic proximity Read ↗

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The lipoprotein lipase Ser447Ter mutation and risk of stroke in the Chinese.Semantic proximity Read ↗

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