Article
Genetic polymorphisms of CYP1A1 in a Korean population.
Archives of toxicology - 1 Jun 2004
Park Duk Woong, Jin Bohwan, Jang Dongdeuk, Yang Kihwa, Park Jung-Duck, Lee Yong-Soon, Ryu Doug-Young
Abstract excerpt
Genetic polymorphisms in the coding exons of the CYP1A1 gene were analyzed in 100 Koreans. Three types of CYP1A1 polymorphisms, specifically G134A, G184C and A2455G, were identified with allelic frequencies of 18, 3, and 16%, respectively, and no linkage was observed among them. The novel G184C polymorphism identified in this study was associated with the mutation of an alanine residue at position 62 to proline....
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