Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Klinefelter Syndrome in Adolescence: Onset of Puberty Is Associated with Accelerated Germ Cell Depletion

1 May 2004

Abstract excerpt

The process of germ cell depletion in patients with Klinefelter syndrome (KS) is incompletely characterized. In the current work, we evaluated the presence of germ cells in adolescent boys with KS for possible future use in assisted reproduction techniques. Fourteen nonmosaic 47,XXY boys (aged 10-14 yr) were enrolled. Every fourth month their puberty was staged, and serum was obtained for hormone analyses. Each...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Sexual Differentiation and Disorders
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15126551
DOI: 10.1210/jc.2003-031725

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Klinefelter Syndrome in Adolescence: Onset of Puberty Is Associated with Accelerated Germ Cell DepletionPMID 15126551Read ↗

Natural history of seminiferous tubule degeneration in Klinefelter syndromeSemantic proximity Read ↗

Gonadal dysfunction and beyond: Clinical challenges in children, adolescents, and adults with 47,<scp>XXY</scp> Klinefelter syndromeSemantic proximity Read ↗

Failure of a combined clinical- and hormonal-based strategy to detect early spermatogenesis and retrieve spermatogonial stem cells in 47,XXY boys by single testicular biopsySemantic proximity Read ↗

Immunoexpression of Androgen Receptor and Nine Markers of Maturation in the Testes of Adolescent Boys with Klinefelter Syndrome: Evidence for Degeneration of Germ Cells at the Onset of MeiosisSemantic proximity Read ↗

Klinefelter syndrome and fertility: sperm preservation should not be offered to children with Klinefelter syndromeSemantic proximity Read ↗

Germ cell loss in Klinefelter syndrome: When and why?Semantic proximity Read ↗

Klinefelter syndrome: the commonest form of hypogonadism, but often overlooked or untreated.Semantic proximity Read ↗

Klinefelter's syndrome: a clinical and therapeutical update.Semantic proximity Read ↗

Testis Development and Fertility Potential in Boys with Klinefelter SyndromeSemantic proximity Read ↗

Blood Testis Barrier and Somatic Cells Impairment in a Series of 35 Adult Klinefelter Syndrome PatientsSemantic proximity Read ↗

Clinical and biological parameters in 166 boys, adolescents and adults with nonmosaic Klinefelter syndrome: a Copenhagen experience.Semantic proximity Read ↗

Therapy of endocrine disease: Testicular function and fertility in men with Klinefelter syndrome: a reviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.