Article
Squamous cell carcinoma related oncogene regulates angiogenesis through vascular endothelial growth factor-A.
Annals of surgical oncology - 1 May 2004
Talbot Simon G, O-charoenrat Pornchai, Sarkaria Inderpal S, Ghossein Ronald, Reddy Pabbathi, Ngai Ivan, Cordeiro Christina N, Wong Richard J, Kris Mark G, Rusch Valerie W, Singh Bhuvanesh
Abstract excerpt
BACKGROUND: Squamous cell carcinoma related oncogene expression (SCCRO) correlates with vascular endothelial growth factor-A expression. This data is validated in human lung tumors and provides a putative pathway for angiogenesis in a subset of squamous cell carcinomas. Squamous cell carcinoma related oncogene is a novel oncogene identified by positional cloning of a recurrent amplification at 3q26.3. It is...
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