Article
Combination therapy with amantadine and interferon in naïve patients with chronic hepatitis C: meta-analysis of individual patient data from six clinical trials.
Journal of hepatology - 1 Mar 2004
Mangia Alessandra, Leandro Gioacchino, Helbling Beat, Renner Eberhard L, Tabone Marco, Sidoli Laura, Caronia Simona, Foster Graham R, Zeuzem Stephan, Berg Thomas, Di Marco Vito, Cino Nicolina, Andriulli Angelo
Abstract excerpt
BACKGROUND/AIMS: In chronic hepatitis C, clinical trials evaluating the efficacy of amantadine (AMA) and interferon (INF) compared to INF monotherapy, have produced conflicting results. We performed a meta-analysis of the individual patient's data from previous studies. METHODS: Nine hundred and seventy-two patients from six European centres were evaluated by means of individual patient meta-analysis, using mixed...
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