No beneficial effects of amantadine in treatment of chronic hepatitis C patients.

doi:10.1016/j.dld.2009.10.006

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Article

No beneficial effects of amantadine in treatment of chronic hepatitis C patients.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Jul 2010

van Soest Hanneke, van der Schaar Peter J, Koek Ger H, de Vries Richard A, van Ooteghem Nancy A, van Hoek Bart, Drenth Joost P H, Vrolijk Jan M, Lieverse Rob J, Houben Peter, van der Sluys Veer Annet, Siersema Peter D, Schipper Marguerite E I, van Erpecum Karel J, Boland Greet J

Abstract excerpt

BACKGROUND: Benefit of adding amantadine to antiviral therapy for hepatitis C is controversial. AIMS: We aimed to examine whether such policy enhances sustained viral response in treatment-naïve patients. METHODS: 297 naïve hepatitis C patients were randomized for treatment with amantadine 200mg or placebo, combined with weight-based ribavirin and 12-day high-dose interferon alpha-2b induction therapy, followed...

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Identifiers

PMID: 20018575
DOI: 10.1016/j.dld.2009.10.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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