Article
Crosslinking of and coupling to viral capsid proteins by tyrosine oxidation.
Chemistry & biology - 1 Mar 2004
Meunier Stéphane, Strable Erica, Finn M G
Abstract excerpt
Cowpea mosaic virus is composed of 60 identical copies of a two-subunit protein organized in pentameric assemblies around the icosahedral 5-fold symmetry axis. Treatment of the virus with the Ni(II) complex of the tripeptide GGH and a peroxide oxidant, or irradiation in the presence of Ru(bpy)(3)(2+) and persulfate generates covalent crosslinks across the pentameric subunit boundaries, effectively stitching the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
