A large case-control study of cervical cancer risk associated with human papillomavirus infection in Japan, by nucleotide sequencing-based genotyping.

doi:10.1086/382896

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Article

A large case-control study of cervical cancer risk associated with human papillomavirus infection in Japan, by nucleotide sequencing-based genotyping.

The Journal of infectious diseases - 15 May 2004

Asato Tsuyoshi, Maehama Toshiyuki, Nagai Yutaka, Kanazawa Koji, Uezato Hiroshi, Kariya Ken-Ichi

Abstract excerpt

Using nucleotide sequencing-based genotyping, we conducted a case-control study to examine cervical cancer risk associated with human papillomavirus (HPV) infection in a Japanese population. A consensus primer pair was used to amplify DNA from the L1 region of HPV by polymerase chain reaction (PCR). By PCR, 311 of 356 patients with cervical cancer and 333 of 3249 control individuals were positive for HPV. By the...

Topics

Adult
Aged
Aged, 80 and over
Carcinoma, Squamous Cell
Case-Control Studies
DNA, Viral
Female
Genotype
Humans
Japan
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Papillomaviridae

Papillomavirus Infections

Polymerase Chain Reaction

Sequence Analysis, DNA

Tumor Virus Infections

Uterine Cervical Neoplasms

Source

Open in PubMed

Identifiers

PMID: 15122519
DOI: 10.1086/382896

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-15122519-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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