Article
Biased amplification of human papillomavirus DNA in specimens containing multiple human papillomavirus types by PCR with consensus primers.
Cancer science - 1 Jun 2011
Mori Seiichiro, Nakao Sari, Kukimoto Iwao, Kusumoto-Matsuo Rika, Kondo Kazunari, Kanda Tadahito
Abstract excerpt
Genotyping human papillomavirus (HPV) in clinical specimens is important because each HPV type has different oncogenic potential. Amplification of HPV DNA by PCR with the consensus primers that are derived from the consensus sequences of the L1 gene has been used widely for the genotyping. As recent studies have shown that the cervical specimens often contain HPV of multiple types, it is necessary to confirm...
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