Article
Variation in the miRNA-433 binding site of FGF20 is a risk factor for Parkinson's disease in Iranian population.
Journal of the neurological sciences - 15 Aug 2015
Haghnejad Leyla, Emamalizadeh Babak, Jamshidi Javad, Bidoki Alireza Zare, Ghaedi Hamid, Ahmadi Ehsan, Abdollahi Shokoufeh, Shahmohammadibeni Neda, Taghavi Shaghayegh, Fazeli Atena, Motallebi Marzieh, Zarneh Amir Ehtesham Shafiei, Mohammadihosseinabad Saeed, Abbaszadegan Mohammad Reza, Torkamandi Shahram, Gavenaroudi Masoumeh Amini, Pedram Negar, Shahidi Gholam-Ali, Tafakhori Abbas, Darvish Hossein, Movafagh Abolfazl
Abstract excerpt
DNA variations in the fibroblast growth factor 20 gene have been reported to be associated with Parkinson's disease (PD). The rs12720208, a functional SNP located in the 3'UTR region of the gene, was reported as a risk factor for PD. A number of studies, which tried to replicate the result in different populations, failed to detect any associations. In this study, we genotyped rs2720208 SNP in 520 PD patients and...
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