Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between variation in the human KCNJ10 potassium ion channel gene and seizure susceptibility.

Epilepsy research - 1 Feb 2004

Buono R J, Lohoff F W, Sander T, Sperling M R, O'Connor M J, Dlugos D J, Ryan S G, Golden G T, Zhao H, Scattergood T M, Berrettini W H, Ferraro T N

Abstract excerpt

PURPOSE: Our research program uses genetic linkage and association analysis to identify human seizure sensitivity and resistance alleles. Quantitative trait loci mapping in mice led to identification of genetic variation in the potassium ion channel gene Kcnj10, implicating it as a putative seizure susceptibility gene. The purpose of this work was to translate these animal model data to a human genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chi-Square Distribution
Share to Confidence Intervals

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Odds Ratio

Share to Potassium Channels

Share to Potassium Channels, Inwardly Rectifying

Share to Quantitative Trait Loci

Share to Seizures

Source

Identifiers

PMID: 15120748
DOI: 10.1016/j.eplepsyres.2004.02.003

Genes

KCNJ10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between variation in the human KCNJ10 potassium ion channel gene and seizure susceptibility.PMID 15120748Read ↗

Supportive evidence for an allelic association of the human KCNJ10 potassium channel gene with idiopathic generalized epilepsy.Semantic proximity Read ↗

Genetic association of KCNJ10 rs1130183 with seizure susceptibility and computational analysis of deleterious non-synonymous SNPs of KCNJ10 gene.Semantic proximity Read ↗

Fine mapping of a seizure susceptibility locus on mouse Chromosome 1: nomination of Kcnj10 as a causative gene.Semantic proximity Read ↗

Common variants of KCNJ10 are associated with susceptibility and anti-epileptic drug resistance in Chinese genetic generalized epilepsies.Semantic proximity Read ↗

Association of KCNJ10 variants and the susceptibility to clinical epilepsy.Semantic proximity Read ↗

Contribution of KCNJ10 gene polymorphisms in childhood epilepsy.Semantic proximity Read ↗

Functional characterisation of missense variations in the Kir4.1 potassium channel (KCNJ10) associated with seizure susceptibility.Semantic proximity Read ↗

Epilepsy, ataxia, sensorineural deafness, tubulopathy, and KCNJ10 mutations.Semantic proximity Read ↗

KCNQ2 and KCNQ3 mutations contribute to different idiopathic epilepsy syndromes.Semantic proximity Read ↗

Novel Mutations in KCNJ10 Gene Associated With SeSAME Syndrome: Rare Disorder With Possible Common Mutation.Semantic proximity Read ↗

A locus on mouse Ch10 influences susceptibility to limbic seizure severity: fine mapping and in silico candidate gene analysis.Semantic proximity Read ↗

Seizure disorders in mutant mice: relevance to human epilepsies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.