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Article

Genetic association of KCNJ10 rs1130183 with seizure susceptibility and computational analysis of deleterious non-synonymous SNPs of KCNJ10 gene.

Gene - 25 Feb 2014

Phani Nagaraja M, Acharya Shreeshakala, Xavy Seethu, Bhaskaranand Nalini, Bhat Manoj K, Jain Aditya, Rai Padmalatha S, Satyamoorthy Kapaettu, Kapaettu Satyamoorthy

Abstract excerpt

Establishing genetic basis of Idiopathic generalized epilepsies (IGE) is challenging because of their complex inheritance pattern and genetic heterogeneity. Kir4.1 inwardly rectifying channel (KCNJ10) is one of the independent genes reported to be associated with seizure susceptibility. In the current study we have performed a comprehensive in silico analysis of genetic variants in KCNJ10 gene at functional and...

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Source

Identifiers

PMID: 24378235
DOI: 10.1016/j.gene.2013.12.026

Genes

KCNJ10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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