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Article

Common variants of KCNJ10 are associated with susceptibility and anti-epileptic drug resistance in Chinese genetic generalized epilepsies.

PloS one - 1 Jan 2015

Guo Yong, Yan Kui Po, Qu Qiang, Qu Jian, Chen Zi Gui, Song Tao, Luo Xiang-Ying, Sun Zhong-Yi, Bi Chang-Long, Liu Jin-Fang

Abstract excerpt

To explore genetic mechanism of genetic generalized epilepsies (GGEs) is challenging because of their complex heritance pattern and genetic heterogeneity. KCNJ10 gene encodes Kir4.1 channels and plays a major role in modulating resting membrane potentials in excitable cells. It may cause GGEs if...

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Source

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Identifiers

PMID: 25874548
DOI: 10.1371/journal.pone.0124896
PMCID: PMC4395153

Genes

KCNJ10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25874548-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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