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Article

Decrease in particle-induced osteolysis in obese (ob/ob) mice.

Biomaterials - 1 Aug 2004

von Knoch M, Jewison D E, Sibonga J D, Turner R T, Morrey B F, Loer F, Berry D J, Scully S P

Abstract excerpt

There may be variability in the susceptibility of different individuals to osteolysis from wear debris, and it is not clear whether some individuals may have a genetic predisposition for a more marked osteolytic response. The purpose of this study in mice was to determine whether genetically determined obesity can alter the response to particulate debris. Polyethylene particles were implanted onto the calvaria of...

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Identifiers

PMID: 15120513
DOI: 10.1016/j.biomaterials.2004.02.069

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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