Article
Association between norepinephrine transporter gene polymorphism and major depression.
Neuropsychobiology - 1 Jan 2004
Ryu Seung-Ho, Lee Seung-Hwan, Lee Heon-Jeong, Cha Ji-Hyun, Ham Byung-Joo, Han Chang-Su, Choi Myoung-Jin, Lee Min-Soo
Abstract excerpt
Noradrenergic and serotonergic abnormalities have long been implicated in patients with major depression. The novel selective norepinephrine reuptake inhibitor reboxetine has been shown to be at least as effective as imipramine, desipramine and fluoxetine in the treatment of major depression. It is suggested that the dysfunction of the norepinephrine transporter (NET) may be related to major depression. Although...
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