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Article

Phenotypic heterogeneity of potentially curable non-small-cell lung cancer: cohort study with cluster analysis.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 May 2015

Sakr Lama, Small David, Kasymjanova Goulnar, Suissa Samy, Ernst Pierre

Abstract excerpt

INTRODUCTION: Significant differences in outcome are observed among lung cancer patients belonging to the same tumor node metastasis stage, suggesting phenotypic heterogeneity beyond this staging algorithm. We used a cluster analysis approach to classify patients into distinct phenotypes, and we attempted to validate the clinical relevance of these phenotypes by comparing outcome. METHODS: We formed a cohort of...

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PMID: 25898956
DOI: 10.1097/JTO.0000000000000505

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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