Article
Role of amino acid residues on the GS region of Stichopus arginine kinase and Danio creatine kinase.
The protein journal - 1 Jan 2004
Uda Kouji, Suzuki Tomohiko
Abstract excerpt
Stichopus arginine kinase (AK) is a unique enzyme in that it evolved not from the AK gene but from the creatine kinase (CK) gene: the entire amino acid sequence is homologous with other CKs apart from the guanidine specificity region (GS region), which is identical in structure to that of AK. Ten independent mutations were introduced around the GS region in Stichopus AK. When an insertion or deletion was...
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