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Article

Mutation of residue arginine 330 of arginine kinase results in the generation of the oxidized form more susceptible.

International journal of biological macromolecules - 1 Mar 2013

Wang Wei-Dong, Wang Jin-Song, Shi Yu-Lin, Zhang Xin-Chao, Pan Ji-Cheng, Zou Guo-Lin

Abstract excerpt

Arginine kinase (AK), a crucial enzyme for the energy metabolism of invertebrates, catalyzes the reversible phosphorylation of arginine by Mg(2+)ATP to form phosphoarginine and Mg(2+)ADP. Arginine 330 (R330), not involved in the catalysis of phosphoryl transfer, is a residue highly conserved in the phosphagen kinase family. In order to investigate the role of R330 in AK, it was replaced by lysine (R330K)....

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PMID: 23262386
DOI: 10.1016/j.ijbiomac.2012.12.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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