Article
The roles of C-terminal loop residues of dimeric arginine kinase from sea cucumber Stichopus japonicus in catalysis, specificity and structure.
International journal of biological macromolecules - 30 May 2006
Zhang Jian-wei, Zhao Tong-jin, Wang Shi-lei, Guo Qin, Liu Tao-tao, Zhao Feng, Wang Xi-cheng
Abstract excerpt
Arginine kinase (AK) catalyzes the reversible phosphorylation of arginine by MgATP to form a high-energy compound phosphoarginine (Parg) and MgADP in forward reaction in invertebrates. To detect the different catalytical mechanisms among Stichopus-AK (dimer) and Limulus-AK (monomer) and Torpedo creatine kinase (dimeric CK) and to reveal the structural role of the C-terminal domain loop (C-loop) of dimeric AK, six...
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