Article
Endothelial dysfunction in patients with asthma: the role of polymorphisms of ACE and endothelial NOS genes.
The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Apr 2004
Yildiz Pinar, Oflaz Huseyin, Cine Naci, Genchallac Hakan, Erginel-Unaltuna Nihan, Yildiz Alaattin, Yilmaz Veysel
Abstract excerpt
OBJECTIVES: Polymorphisms of the angiotensin converting enzyme (ACE) and endothelial nitric oxide (eNOS) genes have been implicated in asthma pathogenesis. Angiotensin II and NO have important roles in maintaining vascular tone. In this study, the relationship between endothelial dysfunction and ACE and eNOS gene polymorphisms was investigated in patients with asthma. METHODS: This cross-sectional, controlled...
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