Article
Common intronic D variant of ACE gene is associated with endothelial dysfunction in COPD.
Respiratory medicine - 1 Aug 2013
Kuzubova Natalia A, Chukhlovin Alexey B, Morozova Elena B, Totolian Areg A, Titova Olga N
Abstract excerpt
BACKGROUND: Pathogenesis of chronic obstructive lung disease (COPD) includes primary inflammatory events, multiple vascular reactions, remodeling of bronchial and vascular walls. OBJECTIVE: The aim of present single-center study was to assess relations between angiotensin-converting enzyme (ACE) gene and prevalence of clinical symptoms characteristic to COPD. METHODS: The study involved sixty-three male patients...
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