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Article

Comparative usage of herpesvirus entry mediator A and nectin-1 by laboratory strains and clinical isolates of herpes simplex virus.

Virology - 1 May 2004

Krummenacher Claude, Baribaud Frédéric, Ponce de Leon Manuel, Baribaud Isabelle, Whitbeck J Charles, Xu Ruliang, Cohen Gary H, Eisenberg Roselyn J

Abstract excerpt

The herpesvirus entry mediator A (HVEM/HveA) and nectin-1 (HveC/CD111) are two major receptors for herpes simplex virus (HSV). Although structurally unrelated, both receptors can independently mediate entry of wild-type (wt) HSV-1 and HSV-2 by interacting with the viral envelope glycoprotein D (gD). Laboratory strains with defined mutations in gD (e.g. rid1) do not use HVEM but use nectin-2 (HveB/CD112) for...

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Identifiers

PMID: 15110526
DOI: 10.1016/j.virol.2004.02.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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