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Article

Nectin-1-specific entry of herpes simplex virus 1 is sufficient for infection of the cornea and viral spread to the trigeminal ganglia.

Molecular vision - 1 Jan 2012

Shukla Navika D, Tiwari Vaibhav, Valyi-Nagy Tibor

Abstract excerpt

PURPOSE: Primary and recurrent infections of the cornea by herpes simplex virus 1 (HSV-1) are important causes of eye disease. Three unrelated classes of glycoprotein D receptors for HSV-1 entry into cells have been identified. This study was undertaken to uncover the relative significance of nectin-1 as an entry receptor in corneal infection and HSV-1 spread to the trigeminal ganglia (TG), a site important for...

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Share to Epithelium, Corneal
Share to Herpes Simplex
Share to Herpesvirus 1, Human

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Nectins

Share to Trigeminal Ganglion

Share to Viral Plaque Assay

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Source

Open in PubMed Open full text

Identifiers

PMID: 23213272
PMCID: PMC3513192

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Nectin-1-specific entry of herpes simplex virus 1 is sufficient for infection of the cornea and viral spread to the trigeminal ganglia.PMID 23213272Read ↗

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