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Article

Association between tau polymorphism and male early-onset Alzheimer's disease.

Neuroreport - 19 Jan 2004

Tanahashi Hiroshi, Asada Takashi, Tabira Takeshi

Abstract excerpt

Neurofibrillary tangles, containing hyperphosphorylated microtubule-associated protein tau, are one of the major pathological hallmarks of Alzheimer's disease. To investigate a possible association between tau genotypes and the risk of Alzheimer's disease, we screened for polymorphisms in the tau gene and found a novel polymorphism IVS11 + 90G --> A. A case-control study (874 patients and 678 controls) showed a...

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Identifiers

PMID: 15106853
DOI: 10.1097/00001756-200401190-00034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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