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Article

Molecular evolution and genetics of the Saitohin gene and tau haplotype in Alzheimer's disease and argyrophilic grain disease.

Journal of neurochemistry - 1 Apr 2004

Conrad Chris, Vianna Cintia, Schultz Christian, Thal Dietmar R, Ghebremedhin Estifanos, Lenz Jack, Braak Heiko, Davies Peter

Abstract excerpt

A single nucleotide polymorphism that results in an amino acid change (Q7R) has been identified in the Saitohin (STH) gene and was initially found to be over-represented in the homozygous state in subjects with late-onset Alzheimer's disease (AD). More extensive studies provide limited support fo...

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Source

Identifiers

PMID: 15030402
DOI: 10.1046/j.1471-4159.2004.02320.x

Genes

STH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15030402-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Molecular evolution and genetics of the Saitohin gene and tau haplotype in Alzheimer's disease and argyrophilic grain disease.PMID 15030402Read ↗

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Sequence analysis of tau 3'untranslated region and saitohin gene in sporadic progressive supranuclear palsy.Semantic proximity Read ↗

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Strong association of the Saitohin gene Q7 variant with progressive supranuclear palsy.Semantic proximity Read ↗

HD phenocopies--possible role of Saitohin gene.Semantic proximity Read ↗

TAU haplotype and the Saitohin Q7R gene polymorphism do not influence CSF Tau in Alzheimer's disease and are not associated with frontotemporal dementia or Parkinson's disease.Semantic proximity Read ↗

Saitohin gene is not associated with Alzheimer's disease.Semantic proximity Read ↗

The Q7R Saitohin gene polymorphism is not associated with Alzheimer disease.Semantic proximity Read ↗

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