Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

T cell response in rheumatic fever: crossreactivity between streptococcal M protein peptides and heart tissue proteins.

Current protein & peptide science - 1 Feb 2007

Guilherme Luiza, Faé Kellen C, Oshiro Sandra E, Tanaka Ana C, Pomerantzeff Pablo M A, Kalil Jorge

Abstract excerpt

Molecular mimicry between streptococcal and human proteins has been proposed as the triggering factor leading to autoimmunity in rheumatic fever (RF) and rheumatic heart disease (RHD). In this review we focus on the studies on genetic susceptibility markers involved in the development of RF/RHD and molecular mimicry mediated by T cell responses of RHD patients against streptococcal antigens and human tissue...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Bacterial
Share to Antigens, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Bacterial Outer Membrane Proteins

Share to Cross Reactions

Share to Immunity, Cellular

Share to Molecular Mimicry

Share to Receptors, Antigen, T-Cell, alpha-beta

Share to Streptococcus pyogenes

Source

Identifiers

PMID: 17305559
DOI: 10.2174/138920307779941488

Genes

RHD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

T cell response in rheumatic fever: crossreactivity between streptococcal M protein peptides and heart tissue proteins.PMID 17305559Read ↗

Molecular pathogenesis of rheumatic fever and rheumatic heart diseaseSemantic proximity Read ↗

T Cell Mimicry and Epitope Specificity of Cross-Reactive T Cell Clones from Rheumatic Heart DiseaseSemantic proximity Read ↗

Rheumatic Fever and Rheumatic Heart Disease: Genetics and PathogenesisSemantic proximity Read ↗

Rheumatic fever and rheumatic heart disease: cellular mechanisms leading autoimmune reactivity and disease.Semantic proximity Read ↗

Rheumatic fever: from sore throat to autoimmune heart lesions.Semantic proximity Read ↗

Rheumatic heart disease: mediation by complex immune events.Semantic proximity Read ↗

Molecular mimicry in the autoimmune pathogenesis of rheumatic heart diseaseSemantic proximity Read ↗

Identification of T cell autoepitopes that cross-react with the C-terminal segment of the M protein of group A streptococciSemantic proximity Read ↗

Rheumatic fever: from innate to acquired immune response.Semantic proximity Read ↗

An immunological perspective on rheumatic heart disease pathogenesis: more questions than answers.Semantic proximity Read ↗

B- and T-Cell Responses in Group A Streptococcus M-Protein- or Peptide-Induced Experimental CarditisSemantic proximity Read ↗

Rheumatic Fever, Autoimmunity, and Molecular Mimicry: The Streptococcal ConnectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.