Article
High baseline interleukine-8 level is an independent risk factor for the achievement of sustained virological response in chronic HCV patients.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Aug 2011
Akbar Haji, Idrees Muhammad, Butt Sadia, Awan Zunaira, Sabar Muhammd Farooq, Rehaman Irshad ur, Hussain Abrar, Saleem Sana
Abstract excerpt
Hepatitis C virus (HCV), a major cause of liver disease throughout the world, is difficult to treat with interferon (IFN) (and various formulations and combinations thereof) being the only approved molecule available. It has been investigated recently that proinflammatory chemokine interleukin-8 (IL-8) induced by HCV partially inhibits the antiviral IFN-α therapy. Therefore, the current study was aimed to...
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