Article
CD158k/KIR3DL2 is a new phenotypic marker of Sezary cells: relevance for the diagnosis and follow-up of Sezary syndrome.
The Journal of investigative dermatology - 1 Mar 2004
Poszepczynska-Guigné Ewa, Schiavon Valérie, D'Incan Michel, Echchakir Hamid, Musette Philippe, Ortonne Nicolas, Boumsell Laurence, Moretta Alessandro, Bensussan Armand, Bagot Martine
Abstract excerpt
CD158k molecules belong to the family of killer cell immunoglobulin-like receptors (KIR) that are expressed on a minor population of circulating NK and CD8+ T lymphocytes. Here, we report a strong positive correlation between the percentage of CD158k+ blood lymphocytes analyzed by flow cytometry and the percentage of atypical circulating cells (Sezary cells) determined by cytomorphology in a large group of...
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