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Article

Cdc42 and mDia3 regulate microtubule attachment to kinetochores.

Nature - 15 Apr 2004

Yasuda Shingo, Oceguera-Yanez Fabian, Kato Takayuki, Okamoto Muneo, Yonemura Shigenobu, Terada Yasuhiko, Ishizaki Toshimasa, Narumiya Shuh

Abstract excerpt

During mitosis, the mitotic spindle, a bipolar structure composed of microtubules (MTs) and associated motor proteins, segregates sister chromatids to daughter cells. Initially some MTs emanating from one centrosome attach to the kinetochore at the centromere of one of the duplicated chromosomes. This attachment allows rapid poleward movement of the bound chromosome. Subsequent attachment of the sister...

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PMID: 15085137
DOI: 10.1038/nature02452

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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