Article
The nonlinear structure of linkage disequilibrium.
Theoretical population biology - 1 Aug 2020
Smith Reginald D
Abstract excerpt
The allele frequency dependence of the ranges of all measures of linkage disequilibrium is well-known. The maximum values of commonly used parameters such as r2 and D vary depending on the allele frequencies at each locus. However, though this phenomenon is recognized and accounted for in many studies, the comprehensive mathematical framework underlying the limits of linkage disequilibrium measures at various...
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