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Article

Zebrafish pitx3 is necessary for normal lens and retinal development.

Mechanisms of development - 1 Apr 2005

Shi Xiaohai, Bosenko D V, Zinkevich N S, Foley S, Hyde D R, Semina E V, Vihtelic Thomas S

Abstract excerpt

The human PITX3 gene encodes a bicoid-like homeodomain transcription factor associated with a variety of congenital ocular conditions, including anterior segment dysgenesis, Peter's anomaly, and cataracts. We identified a zebrafish pitx3 gene encoding a protein (Pitx3) that possesses 63% amino acid identity with human PITX3. The zebrafish pitx3 gene encompasses approximately 16.5kb on chromosome 13 and consists...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15804565
DOI: 10.1016/j.mod.2004.11.012

Genes

PITX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Zebrafish pitx3 is necessary for normal lens and retinal development.PMID 15804565Read ↗

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