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Article

The negative role of cyclin G in ATM-dependent p53 activation.

Oncogene - 8 Jul 2004

Ohtsuka Takao, Jensen Michael R, Kim Hyung Gu, Kim Kyung-Tae, Lee Sam W

Abstract excerpt

Cyclin G is one of the earliest p53 target genes to be identified, but its function in the p53 pathway has been elusive. Although the precise mechanisms of cyclin G in this novel network have not been explored, recent studies have demonstrated that cyclin G is a key regulator of the p53-Mdm2 network. Here we present evidence that cyclin G-mediated p53 regulation is dependent upon the status of...

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Identifiers

PMID: 15077171
DOI: 10.1038/sj.onc.1207693

Genes

ATM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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