Article
A new polymorphism (Ser362Thr) of the L-myc gene is not associated with lung adenocarcinoma risk and prognosis.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Feb 2004
Spinola M, Conti B, Ravagnani F, Fabbri A, Incarbone M, Cataldo I, Pira E, Pelucchi C, La Vecchia C, Dragani T A
Abstract excerpt
The non-coding variation in the second intron of the L-myc gene, generating an EcoRI polymorphism, is associated with lung cancer risk and prognosis. We carried out sequence analysis of the L-myc gene in lung adenocarcinoma (ADCA) patients to identify functional polymorphisms and identified a new single nucleotide polymorphism (SNP) in the third exon of the gene causing a Ser362Thr conservative amino acid change...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.