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Article

Polymorphism in MHC class II transactivator gene is not associated with susceptibility to colorectal cancer in Swedish patients.

Anticancer research - 1 Jan 2000

Mumtaz Melad, Löfgren Sture, Hugander Anders, Dimberg Jan

Abstract excerpt

BACKGROUND: Reduced expression of major histocompatibility complex class II (MHC-II) genes in colorectal cancer (CRC) has been reported. MHC-II transactivator (CIITA), encoded by the MHC2TA gene, is considered to be the master regulator for MHC-II gene expression. A functional single nucleotide p...

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Source

Identifiers

PMID: 18630461

Genes

CIITA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18630461-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Polymorphism in MHC class II transactivator gene is not associated with susceptibility to colorectal cancer in Swedish patients.PMID 18630461Read ↗

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The MHC2TA -168A>G gene polymorphism is not associated with rheumatoid arthritis in Austrian patients.Semantic proximity Read ↗

Single nucleotide polymorphisms in the gene encoding the major histocompatibility complex class II transactivator (CIITA) in systemic lupus erythematosus.Semantic proximity Read ↗

The MHC2TA -168A/G polymorphism and risk for rheumatoid arthritis: a meta-analysis of 6861 patients and 9270 controls reveals no evidence for association.Semantic proximity Read ↗

MHC2TA single nucleotide polymorphism and genetic risk for autoimmune adrenal insufficiency.Semantic proximity Read ↗

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