Apolipoprotein E isoforms, serum cholesterol, and cancer

Abstract excerpt

SIR,—It is unclear whether the relation between low serum cholesterol levels and cancer1 is causal. In many studies occult tumour may have depressed cholesterol levels though in others the relation was found when serum cholesterol had been measured many years before the cancer was diagnosed. The relation is probably not explained by diet, because in the Seven Countries Study cohorts with widely different diets...

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