Article
A case-control study on the effect of apoliprotein E genotype on head and neck cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Nov 2010
De Feo Emma, Rowell Jessica, Cadoni Gabriella, Nicolotti Nicola, Arzani Dario, Giorgio Arianna, Amore Rosarita, Paludetti Gaetano, Ricciardi Gualtiero, Boccia Stefania
Abstract excerpt
BACKGROUND: The apolipoprotein E gene (apoE) has three major isoforms encoded by the ε2, ε3, and ε4 alleles, with the ε4 allele associated with hypercholesterolemia and the ε2 allele with the opposite effect. An inverse relationship between cholesterolemia and head and neck cancer (HNC) has been...
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